Hypertensive drugs, nifedipine flat flat, sustained release tablets, controlled release tablets, different types of differences
Many patients with hypertension are taking nifedipine, nifedipine common life there are three kinds, the first is called nifedipine plain film, the second is called nifedipine, and the third is called nifedipine.
Today we talk about these three kinds of nifedipine, what they have in common? Where is the difference between them again? And how do we choose?
their chemical name called nifedipine, calcium channel blockers are all, by reducing vascular smooth muscle influx of calcium ions and cell functions vasodilatory effect, to achieve the antihypertensive effect.
1. denitration the flat sheet benzene
nifedipine belongs to a flat sheet of short-acting drugs, onset eat quickly, probably onset within a few minutes, if the buccal sublingual onset faster, probably two minutes to take effect.
nifedipine flat sheet but short duration of action, efficacy maintaining time is relatively short, about 4 to 6 to maintain hours. If nifedipine flat sheet, then, according to count 24 hours a day, three times the interval to eat stabilize blood pressure.
Thus, a flat sheet nifedipine less stable control of blood pressure, easily lead to blood pressure fluctuations. Drug eat within 4 to 6 hours, decreased blood pressure, blood efficacy over a rebound may cause fluctuations in blood pressure. And then run into some patients to eat a leak in bursts, blood pressure fluctuations will be greater.
benefits of nifedipine plain film is cheap, a box of one hundred, probably only 3 to 5 dollars.
slow nifedipine release tablets than flat sheet longer duration of action, its effective time will be extended to 10 to 12 hours. According to count 24 hours a day, 2 times a day to eat nifedipine, blood pressure can be stably day.
Of course, the price of nifedipine, a little more expensive than some of the flat sheet.
nifedipine in the production process, will go through a special production process. For example, controlled-release tablets above may be porous, allowing the active ingredients of drugs after 24 hours, a slow uniform release in the gastrointestinal tract, thereby maintaining stable blood pressure.
Of course, the price of nifedipine is relatively expensive, one might be several dollars.
how to choose?
is not recommended to choose nifedipine flat sheet, because it is really easy to cause fluctuations in blood pressure. Not only that, its side effects such as lower extremity edema, facial flushing and rapid heartbeat, obviously a lot more than sustained-release tablets and controlled-release tablets.
nifedipine effect can, the price is relatively inexpensive, are high cost drugs.
effect of nifedipine preferably, one day can be stabilized to take a blood pressure throughout the day, fewer side effects than the flat sheet and tablets. But for patients with less good economic conditions, sustained-release tablets or more appropriate.